Kumasi Asante Kotoko will take on city neigbours Asokwa Deportivo in the round of 32 of the MTN FA Cup competition.
Ashanti Gold have been paired with rivals new Edubiase United.
Hearts of Oak faces a tricky tie against lower division side Bebeto FC.
Full fixtures below:
ZONE ONE
Techiman Eleven Wonders vs Sankara National/ WA Suntaa
Berekum Arsenals vs Bolga Soccer Masters
Kintampo Top Talents vs Kenyansi New Dreams FC
WA All Stars vs Sunyani DC United
Aduana Stars vs Tamale City FC/ Real Tamale United
ZONE TWO
BIS Paradise FC vs Star Madrid FC
Medeama SC vs Winneba United FC
Asokwa Deportivo vs Asante Kotoko SC
Karela United FC vs Unister Academy
Elmina Sharks vs Bibiani Gold Stars
Ashanti Gold vs New Edubiase FC
ZONE THREE
Beberto FC vs Accra Hearts of Oak
Dreams FC vs Liberty Professionals
Akatsi All Stars vs Tema Youth
FC Nania vs Inter Allies FC
WAFA vs Kotoku Royals